Yeah .... I could see that it would be great for large animal wildlife photography especially in low light.

My first "big white" lens was a 300mm f/2.8 and it produced wonderful image quality but after a time I wanted more focal length for birds .... traded it for a 500 f/4 and then finally traded that for a 600 f/4 which is the ultimate bird lens (imho.) but it's size and weight is a significant challenge to travel with and carry in the field.