Originally Posted by andnowimbroke
I think a lot of this depends on your approach and objective. If you start from scratch and decide "I want to take this shot at f/4.5 because that gives the DoF I want", a truly regimented photographer might set their camera for Av f/4.5 and ISO100, then take a test shot. At this point, we have two variables we need to adjust: exposure comp and ISO. Theoretically, the initial preview should be sufficient to adjust exposure comp to preserve shadows while not sacrificing important highlight detail. That leaves only one adjustment, ISO, and the ISO will likely be increased until you achieve a non-shaky shutter speed, a stop-action/artistic shutter speed, a combination of both, or a reasonable tradeoff given the realities of physics and what's in your hand.
If you look at it from another angle, although increasing exposure comp might lead to a softer, blurry, and/or noisy picture, it's extending the shutter time (if everything else stays the same and you're in Av), and that's going to decrease noise in the shadows (you're giving the sensor more photons courtesy of more time).




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