I have never used Datacolor Spyder, but have used many computers with the NVIDIA GeForce cards so a suggestion to make sure the card is not the problem.
I have seen on some machines you log back in, or start up your computer the screen will come up and be bland. It will take a few minutes before the NVIDIA card will kick in and start working. Sometimes it will glitch and not load at all if there is a problem.
Even though you have a new machine, I would check and make sure you have the most up to date driver for the card. Go to NVIDIA to get the update, not Dell.