Hi Liz, welcome!
What is it that you like better in the 650D than the 60D?
I had the same thing a few years ago. My hands where also too big for the 450D so I had a batterygrip with it. When I upgraded to the 50D at that time I didn't require a batterygrip anymore. Also the build was a lot better. This was one of the main reasons to upgrade.
What also a very "big" upgrade is(IMO) is that you will have an extra control wheel. This means you don't have to push a button before you can change your main settings for example. Having a second control wheel really speeds things up. I played with my sisters new 600D yesterday and the lack of the control wheel was pretty annoying for me. But it could be a personal thing.
If I would have to make your choice I'd pick the 60D for the bigger and better build. A second hand/refurbished 50D is also not that bad. However I don't know what you want to do with your camera. Do you take a lot of portrait orientated shots? Do you want to take full advantage of the video-function? Do you have little kids running around or take lots of action-shots? What do you plan to do mostly with the camera?





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