Absolutely! I fit my Thinktank SD Pixel Pocket Rocket with 9 SD cards in the top pocket alongside business cards and an IR trigger, a intervalometer and battery charger or 580EX II in the front pocket, a black rapid RS-7 in the unsecured side pocket, a 17-55mm F/2.8 IS in a lens case on the sliplock attachment, and then my main gripped body with a 70-200mm F/2.8 IS II on camera. It's incredible how much you can fit in these bags, and they're easy to quickly slide out of the way and forget about while out on a hike or shoot.