I just got back from my Alaska trip. I took my
Lowepro Fastpack 350 loaded with:
5D w/grip
1DmkIIn
17-40
24-105
Tamron 70-300mm f/4-5.6 Di VC
50 f1.4
filters/cards/batteries/charges
laptop
I did not take a tripod. This backpack does not have provisions for it but may not be too hard to modify.
I carried it on the plane fitting it overhead. I put it on the scale and it was 38lbs.
It was a bit tight with all the lenses but I made it work. I feel it was a good investment of $140.
Here is a
link to just a few of my 1,500 shots.